Inversion 16 and translocation (16;16) in ANLL M4eo break in the same subregion of the short arm of chromosome 16

Inversion 16 and translocation (16;16) in ANLL M4eo break in the same subregion of the short arm of chromosome 16

Dauwerse et al. reported a new method for rapid detection of the inversion 16 using fluorescent in situ hybridization with the centromeric probe for chromosome 16 (pHUR 195) and two cosmids for the short arm of chromosome 16, the cosmids 36 and 40. We have applied this method to the metaphases of a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancer genetics and cytogenetics 1991-12, Vol.57 (2), p.225-228
Hauptverfasser: Wessels, Hans W., Dauwerse, Hans G., Breuning, Martijn H., Beverstock, Geoffrey C.
Format: Artikel
Sprache:eng
Schlagworte:
chromosome 16
Chromosome Aberrations - pathology
Chromosome Banding
Chromosome Disorders
Chromosome Inversion
Chromosome Mapping
Chromosomes, Human, Pair 16
DNA Probes
Humans
Leukemia, Myeloid, Acute - pathology
Nucleic Acid Hybridization
translocation
Translocation, Genetic
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Dauwerse et al. reported a new method for rapid detection of the inversion 16 using fluorescent in situ hybridization with the centromeric probe for chromosome 16 (pHUR 195) and two cosmids for the short arm of chromosome 16, the cosmids 36 and 40. We have applied this method to the metaphases of a patient with ANLI M4eo and were able to detect the t(16; 16)(p13; q22).
ISSN:0165-4608
1873-4456
DOI:10.1016/0165-4608(91)90156-O