Ganglion cell survival in embryonic rabbit retina transplanted to the midbrain of neonatal rats

Fetal rabbit retinae can grow and differentiate when transplanted to the collicular region of neonatal rats. In addition, the observed survival of retinal ganglion cells within grafts is associated with the extension of axons into the superior colliculus of the host brain, suggesting that the factor...

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Veröffentlicht in:	Experimental brain research 1991-01, Vol.86 (1), p.182-189
Hauptverfasser:	DIXON, G, JERVIE SEFTON, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn - physiology Axons - ultrastructure Biological and medical sciences Cell Differentiation Cell Survival - physiology Degeneration. Regeneration. Wound healing. Graft Female Fetal Tissue Transplantation - physiology Fundamental and applied biological sciences. Psychology Ganglia - cytology Graft Survival - physiology Horseradish Peroxidase Mesencephalon - physiology Neurofibrils - ultrastructure Perfusion Pregnancy Rabbits Rats Retina - transplantation Retinal Ganglion Cells - ultrastructure Superior Colliculi - cytology Transplantation, Heterologous Transplantation, Heterotopic Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Beschreibung
Zusammenfassung:	Fetal rabbit retinae can grow and differentiate when transplanted to the collicular region of neonatal rats. In addition, the observed survival of retinal ganglion cells within grafts is associated with the extension of axons into the superior colliculus of the host brain, suggesting that the factors influencing the guidance of axons and the survival of ganglion cells may be homologous across different mammalian orders.
ISSN:	0014-4819 1432-1106
DOI:	10.1007/BF00231052