New viruses and new disease: mutation, evolution and ecology

New viruses and new disease: mutation, evolution and ecology

Given the extraordinarily high mutation rate of viruses, particularly those with RNA genomes, it is not surprising that new viruses are continually evolving. However, the symptomatology of old viral diseases has remained stable for centuries. The combination of genetic and ecological factors that co...

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Veröffentlicht in:Current opinion in immunology 1991-08, Vol.3 (4), p.518-524
1. Verfasser: Kilbourne, Edwin D
Format: Artikel
Sprache:eng
Schlagworte:
Genes, Viral
Humans
Immune Tolerance - immunology
Immunosuppression - adverse effects
Mutation
Virus Diseases - immunology
Viruses - genetics
Viruses - immunology
Viruses - pathogenicity
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Zusammenfassung:Given the extraordinarily high mutation rate of viruses, particularly those with RNA genomes, it is not surprising that new viruses are continually evolving. However, the symptomatology of old viral diseases has remained stable for centuries. The combination of genetic and ecological factors that constrain as well as facilitate the emergence of new viruses is analyzed.
ISSN:0952-7915
1879-0372
DOI:10.1016/0952-7915(91)90014-R