Identification of twelve new RFLP-markers on chromosome 22q11-qter

We have previously identified and regionally localized 195 chromosome-22-specific DNA markers. We now report restriction fragment length polymorphisms detected by 9 phage markers mapped to 22q11-q12, two cosmid clones mapped to 22q12-q13 and one plasmid mapped to 22q13-qter. These markers may be use...

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Veröffentlicht in:	Human genetics 1991-12, Vol.88 (2), p.135-138
Hauptverfasser:	CARLBOM, E, SUGAWA, N, LARSSON, C, SCAMBLER, P. J, DUMANSKI, J. P, COLLINS, V. P, NORDENSKJÖLD, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biological and medical sciences Blotting, Southern Chromosomes, Human, Pair 22 Cloning, Molecular Cosmids - genetics DNA Restriction Enzymes - metabolism Fundamental and applied biological sciences. Psychology Genetic Markers - genetics Humans Molecular and cellular biology Molecular genetics Polymorphism, Restriction Fragment Length
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Beschreibung
Zusammenfassung:	We have previously identified and regionally localized 195 chromosome-22-specific DNA markers. We now report restriction fragment length polymorphisms detected by 9 phage markers mapped to 22q11-q12, two cosmid clones mapped to 22q12-q13 and one plasmid mapped to 22q13-qter. These markers may be useful tools for mapping disease genes such as the NF2 locus, on chromosome 22.
ISSN:	0340-6717 1432-1203
DOI:	10.1007/BF00206060