Hypoglycaemic activity of Ocimum gratissimum in rats

The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal and diabetic rats by 56 and 68%, respectively.

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Bibliographische Detailangaben
Veröffentlicht in:	Fitoterapia 2000-08, Vol.71 (4), p.444-446
Hauptverfasser:	Aguiyi, J.C, Obi, C.I, Gang, S.S, Igweh, A.C
Format:	Artikel
Sprache:	eng
Schlagworte:	Alloxan Animals Biological and medical sciences Blood Glucose - drug effects Diabetes Mellitus - drug therapy Diabetes Mellitus, Experimental Disease Models, Animal General pharmacology Hypoglycaemic activity Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use Male Medical sciences Medicine, African Traditional Ocimum basilicum Ocimum gratissimum Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - pharmacology Plant Leaves Plants, Medicinal Rats Rats, Wistar
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Beschreibung
Zusammenfassung:	The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal and diabetic rats by 56 and 68%, respectively.
ISSN:	0367-326X
DOI:	10.1016/S0367-326X(00)00143-X