Proportional criterion of metabolic activity and fundamentals of drug dosage

A method for determining the drug dose is proposed, according to which the dose of injected drug is proportional to body weight to the power 2/3. The dosage of narcotic analgesic ketamine is in good agreement with the proposed relationship.

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Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2000-05, Vol.129 (5), p.466-467
Hauptverfasser:	Turkovskii, I I, Kuznetsov, A N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Weight Dogs Dose-Response Relationship, Drug Drug dosages Metabolism Rabbits Rats
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A method for determining the drug dose is proposed, according to which the dose of injected drug is proportional to body weight to the power 2/3. The dosage of narcotic analgesic ketamine is in good agreement with the proposed relationship.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/BF02439804