CONCENTRATION OF ISEPAMICIN SULFATE IN BONE MARROW BLOOD

Fifteen patients who were performed a rotator cuff repair were subjected for the determination of a concentration of isepamicin sulfate (ISP), which was infused intravenously, in venous blood and bone marrow blood. The concentrations were measured at 0, 30, 60 minutes after the injection. There was...

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Veröffentlicht in:	Japanese journal of antibiotics 2000/09/25, Vol.53(9), pp.609-613
Hauptverfasser:	SHIBATA, YOZO, MIDORIKAWA, KOJI, NAITO, MASATOSHI, YATSUNAMI, MOTOKI, HAMADA, KENJI
Format:	Artikel
Sprache:	jpn
Schlagworte:	Adult Aged Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacokinetics Biological Transport Bone Marrow - metabolism Female Gentamicins - administration & dosage Gentamicins - pharmacokinetics Humans Infusions, Intravenous Male Middle Aged Rotator Cuff - surgery Rotator Cuff Injuries Surgical Wound Infection - prevention & control Time Factors
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Beschreibung
Zusammenfassung:	Fifteen patients who were performed a rotator cuff repair were subjected for the determination of a concentration of isepamicin sulfate (ISP), which was infused intravenously, in venous blood and bone marrow blood. The concentrations were measured at 0, 30, 60 minutes after the injection. There was no statistically significance between ISP concentrations in venous and bone marrow blood. This study revealed that the transference of ISP to the bone marrow was excellent.
ISSN:	0368-2781 2186-5477
DOI:	10.11553/antibiotics1968b.53.609