Benzylbenzoate and norlignan glucosides from Curculigo pilosa: structural analysis and in vitro vascular activity

Benzylbenzoate and norlignan glucosides from Curculigo pilosa: structural analysis and in vitro vascular activity

From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, pilosidine, previously obtained only as the tetra- O-methyl derivative, were isolated. Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit...

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Veröffentlicht in:Phytochemistry (Oxford) 2000-11, Vol.55 (5), p.411-417
Hauptverfasser: Palazzino, Giovanna, Galeffi, Corrado, Federici, Elena, Delle Monache, Franco, Francesca Cometa, Maria, Palmery, Maura
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Aorta - drug effects
Aorta - physiology
Benzoates - chemistry
Benzylbenzoate glucosides
Biological and medical sciences
Chemical constitution
Curculigo pilosa
Fundamental and applied biological sciences. Psychology
General pharmacology
Glucosides - chemistry
Glucosides - pharmacology
Hypoxidaceae
In Vitro Techniques
Lignans - chemistry
Magnoliopsida - chemistry
Medical sciences
Molecular Structure
Norlignan glucosides
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Piloside A
Piloside B
Pilosidine
Plant physiology and development
Rabbits
Spectrum Analysis
Vascular activity
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Beschreibung
Zusammenfassung:From the rhizomes of Curculigo pilosa, two benzylbenzoate diglucosides, piloside A and piloside B, and a glucosyl-fused norlignan, pilosidine, previously obtained only as the tetra- O-methyl derivative, were isolated. Pilosidine showed facilitating effect on adrenaline evoked contractions in rabbit aorta isolated preparations.
ISSN:0031-9422
1873-3700
DOI:10.1016/S0031-9422(00)00256-9