Two New Alkaloids from Cigarette Smoke Condensate

Chemical constituents of MeOH extracts of cigarette smoke were studied. Two new alkaloids, named cigatin A (1), 2-(Pyridine-3-yloxy)-benzene-1', 4'-diol and B (2), 2(4-Methyl-pyridin-3-yloxy)-benzene-1', 4'-diol, were isolated from a mainstream condensate of cigarette together wi...

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Veröffentlicht in:	Chemical & pharmaceutical bulletin 2000/12/01, Vol.48(12), pp.1990-1991
Hauptverfasser:	YUN, Young Sook, SUGIMOTO, Naoki, SEKITA, Setsuko, MAITANI, Tamio, YAMADA, Takashi, SATAKE, Motoyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaloid Alkaloids - chemistry Alkaloids - isolation & purification Biological and medical sciences cigarette cigatin A cigatin B Hydroquinones - chemistry Hydroquinones - isolation & purification mainstream Medical sciences Pyridines - chemistry Pyridines - isolation & purification Tars - chemistry Tobacco, tobacco smoking Toxicology
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Beschreibung
Zusammenfassung:	Chemical constituents of MeOH extracts of cigarette smoke were studied. Two new alkaloids, named cigatin A (1), 2-(Pyridine-3-yloxy)-benzene-1', 4'-diol and B (2), 2(4-Methyl-pyridin-3-yloxy)-benzene-1', 4'-diol, were isolated from a mainstream condensate of cigarette together with seven known alkaloids. Their structures were determined on the basis of spectral data and chemical methods.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.48.1990