Genetic Factors in the Genesis of Alzheimer's Disease

: At least four different genes have been identified that are associated with inherited susceptibility to Alzheimer's disease. Some of the genes are highly penetrant (PS1, PS2, bAPP); the other, APOE, is a weaker susceptibility factor. Several additional genes are suspected to exist but have no...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of the New York Academy of Sciences 2000-01, Vol.924 (1), p.1-7
1. Verfasser:	ST GEORGE-HYSLOP, P. H.
Format:	Artikel
Sprache:	eng
Schlagworte:	AD susceptibility genes Alzheimer Disease - etiology Alzheimer Disease - genetics Amyloid-beta hypothesis APOE Brain Chemistry - genetics Familial AD Genetic Predisposition to Disease Humans Inheritance of AD Penetrance Tau protein mutations
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	: At least four different genes have been identified that are associated with inherited susceptibility to Alzheimer's disease. Some of the genes are highly penetrant (PS1, PS2, bAPP); the other, APOE, is a weaker susceptibility factor. Several additional genes are suspected to exist but have not yet been cloned.
ISSN:	0077-8923 1749-6632
DOI:	10.1111/j.1749-6632.2000.tb05552.x