The human cardiac troponin I locus : assignment to chromosome 19p13.2-19q13.2

The human cardiac troponin I locus : assignment to chromosome 19p13.2-19q13.2

The three major troponin I isoforms are encoded by separate genes and are expressed in a muscle-type-specific manner. A human cardiac troponin I cDNA has recently been isolated and used to establish the genomic location of the cardiac troponin I gene locus (designated TNNC1). By somatic cell hybrid...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Human genetics 1991-11, Vol.88 (1), p.101-104
Hauptverfasser: MACGEOCH, C, BARTON, P. J. R, VALLINS, W. J, BHAVSAR, P, SPURR, N. K
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cell Line
Chromosome Mapping
Chromosomes, Human, Pair 19
Classical genetics, quantitative genetics, hybrids
Fundamental and applied biological sciences. Psychology
Genetics of eukaryotes. Biological and molecular evolution
Human
Humans
Myocardium
Troponin - genetics
Troponin I
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The three major troponin I isoforms are encoded by separate genes and are expressed in a muscle-type-specific manner. A human cardiac troponin I cDNA has recently been isolated and used to establish the genomic location of the cardiac troponin I gene locus (designated TNNC1). By somatic cell hybrid analysis, the locus for TNNC1 maps to human chromosome 19 and can be localised to the region p13.2-q13.2.
ISSN:0340-6717
1432-1203
DOI:10.1007/BF00204938