Visualization of the Heart and Determination of Left Ventricular Mass in Rats by Echocardiography

A high-frequency transducer was used to determine the optimal parameters for visualizing the heart in 40 normal Wistar, 15 SHR, and 10 aorta-banded rats. The rats were 5 to 30 weeks old and weighed between 105 and 705 grams. Two-dimensional and M-mode views of the ventricles, atria, valves, and grea...

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Veröffentlicht in:	Japanese Heart Journal 1991, Vol.32(4), pp.481-491
Hauptverfasser:	NAKAMURA, Takashi, SHIMOO, Kazutoshi, KURIBAYASHI, Toshiro, MATSUBARA, Kin-ya, SHIMA, Masami, MATSUMURO, Akiyoshi, AZUMA, Akihiro, KATSUME, Hiroshi, NAKAGAWA, Masao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal model Animals Aorta-banded rat Biological and medical sciences Cardiomegaly - diagnostic imaging Cardiomegaly - physiopathology Cardiovascular system Disease Models, Animal Echocardiography - veterinary Heart Ventricles - anatomy & histology Heart Ventricles - diagnostic imaging Investigative techniques, diagnostic techniques (general aspects) Left ventricular hypertrophy Male Medical sciences Myocardial Contraction Rats Rats, Inbred SHR Rats, Inbred Strains Spontaneously hypertensive rat Transducers - veterinary Ultrasonic investigative techniques Ultrasound imaging
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Zusammenfassung:	A high-frequency transducer was used to determine the optimal parameters for visualizing the heart in 40 normal Wistar, 15 SHR, and 10 aorta-banded rats. The rats were 5 to 30 weeks old and weighed between 105 and 705 grams. Two-dimensional and M-mode views of the ventricles, atria, valves, and great arteries were obtained by placing the transducer beneath the rats through the left or right parasternal window in either the prone or the right decubitus positions, respectively. Left ventricular (LV) mass was determined on the basis of a spheroid model; these values correlated well with the LV weight for both the Wistar rats (r=0.94, p
ISSN:	0021-4868 1348-673X
DOI:	10.1536/ihj.32.481