MASIA: recognition of common patterns and properties in multiple aligned protein sequences

MASIA is a software tool for pattern recognition in multiple aligned protein sequences. MASIA converts a sequence to a properties matrix that can be scanned in both vertical and horizontal steps. Consistent patterns are recognized based on the statistical significance of their occurrence. Preset macros can be altered on-line to seek any combination of amino acid properties or sequence characteristics. MASIA output can be used directly by our programs to predict the 3D structure of proteins. Availability: Access MASIA at http://www.scsb.utmb.edu/masia/masia.html. Contact: werner@newton.utmb.edu To whom correspondence should be addressed.