Biomarkers of oxidative stress: an analytical approach

Biomarkers of oxidative stress: an analytical approach

Oxidative stress is implicated in many pathological processes and results from a disruption of the prooxidant/antioxidant balance. This review will focus on noninvasive biomarkers of radical-induced damage in biological fluids and particularly in blood. Special attention will be addressed to new ana...

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Veröffentlicht in:Current opinion in clinical nutrition and metabolic care 2000-09, Vol.3 (5), p.373-384
Hauptverfasser: Thérond, Patrice, Bonnefont-Rousselot, Dominique, Davit-Spraul, Anne, Conti, Marc, Legrand, Alain
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antioxidants - metabolism
Biomarkers - analysis
Biomarkers - blood
DNA - analysis
DNA - metabolism
Humans
Lipid Metabolism
Lipids - analysis
Oxidation-Reduction
Oxidative Stress - physiology
Proteins - analysis
Proteins - metabolism
Sensitivity and Specificity
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Beschreibung
Zusammenfassung:Oxidative stress is implicated in many pathological processes and results from a disruption of the prooxidant/antioxidant balance. This review will focus on noninvasive biomarkers of radical-induced damage in biological fluids and particularly in blood. Special attention will be addressed to new analytical methods for the measurement of radical-mediated alterations in the integrity of lipids, proteins and DNA.
ISSN:1363-1950
1473-6519
DOI:10.1097/00075197-200009000-00009