Low Birth Weight and Dental Fluorosis: Is There an Association?

Objective: The association between low birth weight and dental fluorosis was explored in a cross‐sectional study to explain the higher prevalence of dental fluorosis among African‐American children. Methods: Birth weight data on 960 children were obtained from the New York State Birth Registry. Data on race, fluoride exposure, sociodemographic characteristics, and dental fluorosis were available from a cross‐sectional study conducted in Newburgh and Kingston. Associations among birth weight, race, and fluoride exposure from fluoridated water, regular use of supplements, brushing before the age of 2 years, and subject‐level dental fluorosis were explored using logistic regression procedures. Results: The regression coefficients for the main effects and the two‐way interaction effects associated with low birth weight, race, and fluoride exposure were not statistically significant. Even after controlling for low birth weight and fluoride exposure, African‐American children had a statistically significant higher odds ratio (OR=2.0). An analysis of the data limited to mandibular permanent first molars showed similar effects, except for evidence of effect modification in low birth weight children exposed to fluoride supplements. Conclusions: Lower birth weight did not explain the higher prevalence of dental fluorosis observed among African‐American children.