Frequency, risk factors, and clinical outcomes of left ventricular assist device-associated ventricular thrombus

Frequency, risk factors, and clinical outcomes of left ventricular assist device-associated ventricular thrombus

A retrospective, transesophageal study of 51 consecutive patients receiving a left ventricular (LV) assist device (AD) over a 2-year period showed that LVAD-associated LV thrombosis (16%) was predicted by acute myocardial infarction, atrial cannulation, and postimplantation bleeding, and was associa...

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Veröffentlicht in:The American journal of cardiology 2000-11, Vol.86 (10), p.1156-1159
Hauptverfasser: Reilly, Muredach P., Wiegers, Susan E., Cucchiara, Andrew J., O’Hara, Mary Lou, Plappert, Theodore J., Loh, Evan, Acker, Michael A., St. John Sutton, Martin
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Analysis of Variance
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Clinical outcomes
Coronary Disease - complications
Coronary Disease - therapy
Echocardiography, Transesophageal
Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care
Equipment Failure
Female
Heart attacks
Heart Diseases - diagnostic imaging
Heart Diseases - etiology
Heart Diseases - mortality
Heart Diseases - therapy
Heart Ventricles
Heart-Assist Devices - adverse effects
Humans
Incidence
Intensive care medicine
Logistic Models
Male
Medical sciences
Middle Aged
Patients
Predictive Value of Tests
Retrospective Studies
Risk Factors
Studies
Thrombosis - diagnostic imaging
Thrombosis - etiology
Thrombosis - mortality
Thrombosis - therapy
Treatment Outcome
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Beschreibung
Zusammenfassung:A retrospective, transesophageal study of 51 consecutive patients receiving a left ventricular (LV) assist device (AD) over a 2-year period showed that LVAD-associated LV thrombosis (16%) was predicted by acute myocardial infarction, atrial cannulation, and postimplantation bleeding, and was associated with a fourfold increased risk of stroke compared with patients without thrombosis. LV cannulation, when using short-term LVADs, may decrease the incidence of LV thrombosis, and early transition to Heartmate-LVAD support may improve outcome.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(00)01182-6