Plants as a source of research in antiviral activity. Example of the Haemanthus albiflos bulb

The antiviral potency of an hydroalcoholic extract from Haemanthus albiflos (AMARYLLIDACEAE) bulb was investigated. Experimentations were conducted on continuous cell lines (BGM, MA 104, Hep 2) seeded in microplates. Three viruses from the RNA group (Poliovirus type I, Vesicular Stomatitis Virus typ...

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Veröffentlicht in:	Bulletin de l'Académie nationale de médecine 1991-03, Vol.175 (3), p.439-452
Hauptverfasser:	Husson, G P, Vilaginès, P, Sarrette, B, Vilaginès, R
Format:	Artikel
Sprache:	fre
Schlagworte:	Cell Line - drug effects DNA Viruses - drug effects DNA Viruses - pathogenicity Drug Evaluation, Preclinical Microbial Sensitivity Tests Plant Extracts - pharmacology RNA Viruses - drug effects RNA Viruses - pathogenicity
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Beschreibung
Zusammenfassung:	The antiviral potency of an hydroalcoholic extract from Haemanthus albiflos (AMARYLLIDACEAE) bulb was investigated. Experimentations were conducted on continuous cell lines (BGM, MA 104, Hep 2) seeded in microplates. Three viruses from the RNA group (Poliovirus type I, Vesicular Stomatitis Virus type 11 and Simian Rotavirus SA 11) and two from the DNA group (Adenovirus type 5, Herpes Simplex Virus type 1) were tested. Important reduction in yield of viral infectivity was observed with the RNA group (respectively 6,4 and 4,5 logarithmic units order of magnitude).
ISSN:	0001-4079