Pathogenesis of Proteus mirabilis urinary tract infection

Proteus mirabilis is a causative agent of cystitis and pyelonephritis primarily in individuals with indwelling catheters or structural abnormalities of the urinary tract. The organism produces a variety of unique virulence factors that contribute to its pathogenicity and persistence in the human hos...

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Veröffentlicht in:	Microbes and infection 2000-10, Vol.2 (12), p.1497-1505
Hauptverfasser:	COKER, Christopher, POORE, Carrie A, XIN LI, MOBLEY, Harry L. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Amidohydrolases - metabolism Bacterial diseases Bacterial diseases of the urinary system Biological and medical sciences Female Human bacterial diseases Humans Immunoglobulin A - metabolism Infectious diseases Iron - metabolism Male Medical sciences Metalloendopeptidases - physiology Proteus Infections - immunology Proteus Infections - metabolism Proteus Infections - microbiology Proteus mirabilis Proteus mirabilis - metabolism Proteus mirabilis - pathogenicity Pyelonephritis - metabolism Pyelonephritis - microbiology Urinary Bladder - microbiology Urinary Tract Infections - immunology Urinary Tract Infections - metabolism Urinary Tract Infections - microbiology virulence factors
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Beschreibung
Zusammenfassung:	Proteus mirabilis is a causative agent of cystitis and pyelonephritis primarily in individuals with indwelling catheters or structural abnormalities of the urinary tract. The organism produces a variety of unique virulence factors that contribute to its pathogenicity and persistence in the human host.
ISSN:	1286-4579 1769-714X
DOI:	10.1016/S1286-4579(00)01304-6