Structural genomics projects in Japan

Two major structural genomics projects exist in Japan. The oldest, the RIKEN Structural Genomics Initiative, has two major goals: to determine bacterial, mammalian, and plant protein structures by X-ray crystallography and NMR spectroscopy and to perform functional analyses with the target proteins....

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Veröffentlicht in:	Nature structural & molecular biology 2000-11, Vol.7 Suppl (11s), p.943-945
Hauptverfasser:	Yokoyama, S, Hirota, H, Kigawa, T, Yabuki, T, Shirouzu, M, Terada, T, Ito, Y, Matsuo, Y, Kuroda, Y, Nishimura, Y, Kyogoku, Y, Miki, K, Masui, R, Kuramitsu, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Proteins - chemistry Bacterial Proteins - genetics Bacterial Proteins - metabolism Cell-Free System Computational Biology - economics Computational Biology - manpower Computational Biology - methods Crystallography Crystallography, X-Ray Genomics Genomics - methods Humans Internet Japan Magnetic resonance spectroscopy Membrane proteins Nuclear Magnetic Resonance, Biomolecular Plant Proteins - chemistry Plant Proteins - genetics Plant Proteins - metabolism Protein Biosynthesis Protein Conformation Protein structure Proteins - chemistry Proteins - genetics Proteins - metabolism Structural genomics Structure-Activity Relationship X-ray crystallography
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Beschreibung
Zusammenfassung:	Two major structural genomics projects exist in Japan. The oldest, the RIKEN Structural Genomics Initiative, has two major goals: to determine bacterial, mammalian, and plant protein structures by X-ray crystallography and NMR spectroscopy and to perform functional analyses with the target proteins. The newest, the structural genomics project at the Biological Information Research Center, focuses on human membrane proteins.
ISSN:	1072-8368 1545-9993 1545-9985
DOI:	10.1038/80712