Chronic ethanol exposure in rats affects rabs-dependent hepatic trafficking of apolipoprotein E and transferrin

Because of the important roles of rabs in protein trafficking, we tested whether chronic ethanol exposure affected the trafficking of newly synthesized apolipoprotein E (apoE) or transferrin ( O-glycosylated and N-glycosylated proteins, respectively) attached to acylated or prenylated rabs. The in v...

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Veröffentlicht in:	Alcohol (Fayetteville, N.Y.) N.Y.), 2001-11, Vol.25 (3), p.195-200
Hauptverfasser:	Marmillot, Philippe, Rao, Manjunath N., Lakshman, M.Raj
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism Alcoholism and acute alcohol poisoning Animals ApoE Apolipoproteins E - metabolism Biological and medical sciences Central Nervous System Depressants - pharmacology Endoplasmic Reticulum - drug effects Endoplasmic Reticulum - metabolism Ethanol - pharmacology Golgi Apparatus - drug effects Golgi Apparatus - metabolism Intracellular Fluid - metabolism Liver - drug effects Liver - metabolism Male Medical sciences Protein trafficking Protein Transport - drug effects Protein Transport - physiology rab GTP-Binding Proteins - physiology Rabs Rats Rats, Inbred WF Toxicology Transferrin Transferrin - metabolism
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