A Case of Vesiculo‐Bullous Darier's Disease Associated with Bipolar Psychiatric Disorder
We describe the case of a 71‐year‐old men suffering from Darier's disease since his youth and presenting with intensely itching, vesicular and pustular lesions, localized on his arms, legs and on the ulnar side of his right hand. The patient also had a 30 year‐history of bipolar psychiaric diso...
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Veröffentlicht in: | Journal of dermatology 2000-10, Vol.27 (10), p.673-676 |
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creator | Mei, Sandra Amato, Lauretta Gallerani, Isabella Perrella, Esterina Caproni, Marzia Palleschi, Giovanni Maria Fabbri, Paolo |
description | We describe the case of a 71‐year‐old men suffering from Darier's disease since his youth and presenting with intensely itching, vesicular and pustular lesions, localized on his arms, legs and on the ulnar side of his right hand. The patient also had a 30 year‐history of bipolar psychiaric disorders. The histopathological examination of lesional skin showed suprabasal acantholytic clefting, hyperparakeratosis, and dyskeratosis. Histopathological and immunopathological (direct and indirect immunofluorescence) results, were consistent with vesiculo‐bullous Darier's disease. Corticosteroid therapy with methylprednisolone at low dosage (0.2 mg/kg/day) was started with a quick resolution of the vesicular lesions on his arms and legs. |
doi_str_mv | 10.1111/j.1346-8138.2000.tb02252.x |
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The patient also had a 30 year‐history of bipolar psychiaric disorders. The histopathological examination of lesional skin showed suprabasal acantholytic clefting, hyperparakeratosis, and dyskeratosis. Histopathological and immunopathological (direct and indirect immunofluorescence) results, were consistent with vesiculo‐bullous Darier's disease. Corticosteroid therapy with methylprednisolone at low dosage (0.2 mg/kg/day) was started with a quick resolution of the vesicular lesions on his arms and legs.</description><identifier>ISSN: 0385-2407</identifier><identifier>EISSN: 1346-8138</identifier><identifier>DOI: 10.1111/j.1346-8138.2000.tb02252.x</identifier><identifier>PMID: 11092274</identifier><language>eng</language><publisher>England</publisher><subject>Aged ; Anti-Inflammatory Agents - therapeutic use ; Bipolar Disorder - complications ; bipolar psychiatric disorder ; Darier Disease - complications ; Darier Disease - diagnosis ; Darier Disease - drug therapy ; Darier Disease - pathology ; Diagnosis, Differential ; Extremities ; Fluorescent Antibody Technique ; Glucocorticoids - therapeutic use ; Humans ; Male ; Methylprednisolone - therapeutic use ; systemic corticosteroid therapy ; vesiculo‐bullous Darier's disease</subject><ispartof>Journal of dermatology, 2000-10, Vol.27 (10), p.673-676</ispartof><rights>2000 Japanese Dermatological Association</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2872-b01d1611bb9cd487a1b05dd3bcb427edb863cf98141dc7da72b273c6d3fcf1b43</citedby><cites>FETCH-LOGICAL-c2872-b01d1611bb9cd487a1b05dd3bcb427edb863cf98141dc7da72b273c6d3fcf1b43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1346-8138.2000.tb02252.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1346-8138.2000.tb02252.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11092274$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mei, Sandra</creatorcontrib><creatorcontrib>Amato, Lauretta</creatorcontrib><creatorcontrib>Gallerani, Isabella</creatorcontrib><creatorcontrib>Perrella, Esterina</creatorcontrib><creatorcontrib>Caproni, Marzia</creatorcontrib><creatorcontrib>Palleschi, Giovanni Maria</creatorcontrib><creatorcontrib>Fabbri, Paolo</creatorcontrib><title>A Case of Vesiculo‐Bullous Darier's Disease Associated with Bipolar Psychiatric Disorder</title><title>Journal of dermatology</title><addtitle>J Dermatol</addtitle><description>We describe the case of a 71‐year‐old men suffering from Darier's disease since his youth and presenting with intensely itching, vesicular and pustular lesions, localized on his arms, legs and on the ulnar side of his right hand. The patient also had a 30 year‐history of bipolar psychiaric disorders. The histopathological examination of lesional skin showed suprabasal acantholytic clefting, hyperparakeratosis, and dyskeratosis. Histopathological and immunopathological (direct and indirect immunofluorescence) results, were consistent with vesiculo‐bullous Darier's disease. Corticosteroid therapy with methylprednisolone at low dosage (0.2 mg/kg/day) was started with a quick resolution of the vesicular lesions on his arms and legs.</description><subject>Aged</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Bipolar Disorder - complications</subject><subject>bipolar psychiatric disorder</subject><subject>Darier Disease - complications</subject><subject>Darier Disease - diagnosis</subject><subject>Darier Disease - drug therapy</subject><subject>Darier Disease - pathology</subject><subject>Diagnosis, Differential</subject><subject>Extremities</subject><subject>Fluorescent Antibody Technique</subject><subject>Glucocorticoids - therapeutic use</subject><subject>Humans</subject><subject>Male</subject><subject>Methylprednisolone - therapeutic use</subject><subject>systemic corticosteroid therapy</subject><subject>vesiculo‐bullous Darier's disease</subject><issn>0385-2407</issn><issn>1346-8138</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkEtOwzAQhi0EoqVwBRSxgFWCPU7ilBV98VIlWAALNpZfEa5SUuxEbXccgTNyEhJawRpvPBp_84_8IXRCcESacz6LCI3TMCM0iwBjHFUSAyQQrXZQ9_dpF3UxzZIQYsw66MD7GcbQTwjeRx1CcB-AxV30MghGwpugzINn462qi_Lr43NYF0VZ-2AsnDXurCmsNy028L5UVlRGB0tbvQZDuygL4YIHv1avTd9Z1bKl08Ydor1cFN4cbe8eerqaPI5uwun99e1oMA0VZAxCiYkmKSFS9pWOMyaIxInWVCoZAzNaZilVeT8jMdGKacFAAqMq1TRXOZEx7aHTTe7Cle-18RWfW69MUYg303yCM4ghSQEa8GIDKld670zOF87OhVtzgnlrls94q4-3-nhrlm_N8lUzfLzdUsu50X-jW5UNcLkBlrYw639E87vx5Kek39dYins</recordid><startdate>200010</startdate><enddate>200010</enddate><creator>Mei, Sandra</creator><creator>Amato, Lauretta</creator><creator>Gallerani, Isabella</creator><creator>Perrella, Esterina</creator><creator>Caproni, Marzia</creator><creator>Palleschi, Giovanni Maria</creator><creator>Fabbri, Paolo</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200010</creationdate><title>A Case of Vesiculo‐Bullous Darier's Disease Associated with Bipolar Psychiatric Disorder</title><author>Mei, Sandra ; Amato, Lauretta ; Gallerani, Isabella ; Perrella, Esterina ; Caproni, Marzia ; Palleschi, Giovanni Maria ; Fabbri, Paolo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2872-b01d1611bb9cd487a1b05dd3bcb427edb863cf98141dc7da72b273c6d3fcf1b43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Aged</topic><topic>Anti-Inflammatory Agents - therapeutic use</topic><topic>Bipolar Disorder - complications</topic><topic>bipolar psychiatric disorder</topic><topic>Darier Disease - complications</topic><topic>Darier Disease - diagnosis</topic><topic>Darier Disease - drug therapy</topic><topic>Darier Disease - pathology</topic><topic>Diagnosis, Differential</topic><topic>Extremities</topic><topic>Fluorescent Antibody Technique</topic><topic>Glucocorticoids - therapeutic use</topic><topic>Humans</topic><topic>Male</topic><topic>Methylprednisolone - therapeutic use</topic><topic>systemic corticosteroid therapy</topic><topic>vesiculo‐bullous Darier's disease</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mei, Sandra</creatorcontrib><creatorcontrib>Amato, Lauretta</creatorcontrib><creatorcontrib>Gallerani, Isabella</creatorcontrib><creatorcontrib>Perrella, Esterina</creatorcontrib><creatorcontrib>Caproni, Marzia</creatorcontrib><creatorcontrib>Palleschi, Giovanni Maria</creatorcontrib><creatorcontrib>Fabbri, Paolo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mei, Sandra</au><au>Amato, Lauretta</au><au>Gallerani, Isabella</au><au>Perrella, Esterina</au><au>Caproni, Marzia</au><au>Palleschi, Giovanni Maria</au><au>Fabbri, Paolo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case of Vesiculo‐Bullous Darier's Disease Associated with Bipolar Psychiatric Disorder</atitle><jtitle>Journal of dermatology</jtitle><addtitle>J Dermatol</addtitle><date>2000-10</date><risdate>2000</risdate><volume>27</volume><issue>10</issue><spage>673</spage><epage>676</epage><pages>673-676</pages><issn>0385-2407</issn><eissn>1346-8138</eissn><abstract>We describe the case of a 71‐year‐old men suffering from Darier's disease since his youth and presenting with intensely itching, vesicular and pustular lesions, localized on his arms, legs and on the ulnar side of his right hand. The patient also had a 30 year‐history of bipolar psychiaric disorders. The histopathological examination of lesional skin showed suprabasal acantholytic clefting, hyperparakeratosis, and dyskeratosis. Histopathological and immunopathological (direct and indirect immunofluorescence) results, were consistent with vesiculo‐bullous Darier's disease. Corticosteroid therapy with methylprednisolone at low dosage (0.2 mg/kg/day) was started with a quick resolution of the vesicular lesions on his arms and legs.</abstract><cop>England</cop><pmid>11092274</pmid><doi>10.1111/j.1346-8138.2000.tb02252.x</doi><tpages>4</tpages></addata></record> |
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subjects | Aged Anti-Inflammatory Agents - therapeutic use Bipolar Disorder - complications bipolar psychiatric disorder Darier Disease - complications Darier Disease - diagnosis Darier Disease - drug therapy Darier Disease - pathology Diagnosis, Differential Extremities Fluorescent Antibody Technique Glucocorticoids - therapeutic use Humans Male Methylprednisolone - therapeutic use systemic corticosteroid therapy vesiculo‐bullous Darier's disease |
title | A Case of Vesiculo‐Bullous Darier's Disease Associated with Bipolar Psychiatric Disorder |
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