Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice

The antidiabetic activity of Momordica charantia L. (Cucurbitaceae) was investigated in KK-Ay mice, an animal model with type 2 diabetes with hyperinsulinemia. The water extract of the fruit of Momordica charantia L. (MC) reduced the blood glucose of KK-Ay mice 3 weeks after oral administration (p

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Veröffentlicht in:	Journal of Nutritional Science and Vitaminology 2001, Vol.47(5), pp.340-344
Hauptverfasser:	Miura, T. (Suzuka Univ. of Medical Science, Mie (Japan)), Itoh, C, Iwamoto, N, Kato, M, Kawai, M, Park, S.R, Suzuki, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Biological and medical sciences Blood Glucose - analysis Blood Glucose - drug effects Cell Membrane - metabolism Cucurbitaceae DIABETES Diabetes Mellitus, Type 2 - drug therapy Disease Models, Animal FRUITS General pharmacology Glucose Transporter Type 4 GLUT4 Hyperinsulinism - drug therapy HYPOGLYCAEMIA Hypoglycemic Agents - therapeutic use hypoglycemic effect Insulin - blood Insulin Resistance Male Medical sciences Mice MOMORDICA Momordica charantia Momordica charantia - chemistry Monosaccharide Transport Proteins - metabolism Muscle Proteins Muscle, Skeletal - metabolism Muscle, Skeletal - ultrastructure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - pharmacology Plant Extracts - therapeutic use RATS
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Zusammenfassung:	The antidiabetic activity of Momordica charantia L. (Cucurbitaceae) was investigated in KK-Ay mice, an animal model with type 2 diabetes with hyperinsulinemia. The water extract of the fruit of Momordica charantia L. (MC) reduced the blood glucose of KK-Ay mice 3 weeks after oral administration (p
ISSN:	0301-4800 1881-7742
DOI:	10.3177/jnsv.47.340