Friulimicins: Novel Lipopeptide Antibiotics with Peptidoglycan Synthesis Inhibiting Activity from Actinoplanes friuliensis sp. nov: I. Taxonomic Studies of the Producing Microorganism and Fermentation

A strain that produces new lipopeptide antibiotics is a new species of the genus Actinoplanes for which we propose the name Actinoplanes friuliensis (type strain: HAG 010964). The strain is an actinoplanete actinomycete having cell wall II composition and forming sporangia. Comparisons with Actinopl...

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Veröffentlicht in:	Journal of antibiotics 2000/08/25, Vol.53(8), pp.807-815
Hauptverfasser:	ARETZ, W., MEIWES, J., SEIBERT, G., VOBIS, G., WINK, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales - classification Actinomycetales - metabolism Actinomycetales - physiology Actinoplanes friuliensis Anti-Bacterial Agents - metabolism Anti-Bacterial Agents - pharmacology Antibiotics (antibacterial agents, antifungal agents) Antibiotics, microbial producers, chemotherapic agents, antiseptics, disinfecting agents Applied microbiology Biological and medical sciences Drug Evaluation, Preclinical - methods Fatty Acids - metabolism Fermentation friulimicins Fundamental and applied biological sciences. Psychology lipopeptide antibiotics Microbial Sensitivity Tests Microbiology Peptidoglycan - biosynthesis Peptidoglycan - drug effects peptidoglycans Protein Synthesis Inhibitors - metabolism Protein Synthesis Inhibitors - pharmacology
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Zusammenfassung:	A strain that produces new lipopeptide antibiotics is a new species of the genus Actinoplanes for which we propose the name Actinoplanes friuliensis (type strain: HAG 010964). The strain is an actinoplanete actinomycete having cell wall II composition and forming sporangia. Comparisons with Actinoplanes spp. which have similarities with our isolate, including fatty acid analysis, showed that the isolate belongs to a new species. Taxonomic studies and fermentation are presented.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.53.807