Polymorphisms of human SP-A, SP-B, and SP-D genes: association of SP-B Thr131Ile with ARDS

An allele association study of 19 polymorphisms in surfactant proteins SP‐A1, SP‐A2, SP‐B, and SP‐D genes in acute respiratory distress syndrome (ARDS) was carried out. Trend‐test analysis revealed differences (p

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Bibliographische Detailangaben
Veröffentlicht in:	Clinical genetics 2000-09, Vol.58 (3), p.181-191
Hauptverfasser:	Lin, Z, Pearson, C, Chinchilli, V, Pietschmann, SM, Luo, J, Pison, U, Floros, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino Acid Substitution - genetics Base Sequence Biological and medical sciences DNA Primers Exons - genetics Gene Frequency - genetics genetic markers Genotype Germany Glycoproteins - genetics Humans Infant, Newborn Logistic Models Lung - metabolism Lung - pathology lung disease Medical sciences Microsatellite Repeats - genetics Pneumology Polymorphism, Genetic - genetics Proteolipids - genetics Pulmonary Surfactant-Associated Protein A Pulmonary Surfactant-Associated Protein D Pulmonary Surfactant-Associated Proteins Pulmonary Surfactants - genetics Respiratory Distress Syndrome, Newborn - genetics Respiratory system : syndromes and miscellaneous diseases surfactant protein
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Zusammenfassung:	An allele association study of 19 polymorphisms in surfactant proteins SP‐A1, SP‐A2, SP‐B, and SP‐D genes in acute respiratory distress syndrome (ARDS) was carried out. Trend‐test analysis revealed differences (p
ISSN:	0009-9163 1399-0004
DOI:	10.1034/j.1399-0004.2000.580305.x