Serological HLA class I alleles in Senegalese blood donors detected HBs Ag positive

Serological HLA class I alleles in Senegalese blood donors detected HBs Ag positive

We analysed the HLA class I alleles in 96 blood donors HBs Ag positive compared with 93 healthy control individuals (HBs negative). The most frequent HLA-A, -B, -C alleles found were, A23 (33.6%); A2 (25%); A30 (25%); B8 (31.5%); B7 (16.3%); B58 (11.9%); B35 (11.9%); B49 (11.9%); B53 (10.8%); Cw7 (3...

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Veröffentlicht in:Immunology letters 2000-11, Vol.74 (3), p.229-232
Hauptverfasser: Obami-Itou, Victorie, Barry, Mamadou Farba, Raphenon, George, Thiam, Alassane, Ndiaye, Rokhaya, Ndiaye, Mouhamadou, Diaw, Mouhamed Lamine, Diakhate, Lamine, Dieye, Alioune
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Blood Donors
Carrier State - epidemiology
Female
Gene Frequency
Genes, MHC Class I
Genetic Predisposition to Disease
Genotype
HBe antigen
HBs antigen
Hepatitis B - epidemiology
Hepatitis B - genetics
Hepatitis B e Antigens - blood
hepatitis B surface antigen
Hepatitis B Surface Antigens - blood
hepatitis B virus
histocompatibility locus HLA
HLA alleles
HLA-A1 Antigen - analysis
HLA-A1 Antigen - genetics
HLA-B8 Antigen - analysis
HLA-B8 Antigen - genetics
Humans
Male
Odds Ratio
Senegal
Senegal - epidemiology
Seroepidemiologic Studies
Sénégal
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Zusammenfassung:We analysed the HLA class I alleles in 96 blood donors HBs Ag positive compared with 93 healthy control individuals (HBs negative). The most frequent HLA-A, -B, -C alleles found were, A23 (33.6%); A2 (25%); A30 (25%); B8 (31.5%); B7 (16.3%); B58 (11.9%); B35 (11.9%); B49 (11.9%); B53 (10.8%); Cw7 (39.1%); Cw3 (36.9%); Cw4 (36.9%). Significant differences ( P
ISSN:0165-2478
1879-0542
DOI:10.1016/S0165-2478(00)00272-8