Acquired Robertsonian translocations in two leukemia patients
Robertsonian translocations were observed in two leukemia patients. The first case was a patient with chronic lymphocytic leukemia, who was found to have a rare Robertsonian translocation der(14;15)(q10;q10). The second case, a patient with acute myeloid leukemia, had multiple Robertsonian transloca...
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| Veröffentlicht in: | Cancer genetics and cytogenetics 2001-12, Vol.131 (2), p.104-108 |
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| container_title | Cancer genetics and cytogenetics |
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| creator | Chinnappan, Dharmaraj Philip, Abraham Wu, Xiao Pan, Agen Wyandt, Herman E. |
| description | Robertsonian translocations were observed in two leukemia patients. The first case was a patient with chronic lymphocytic leukemia, who was found to have a rare Robertsonian translocation der(14;15)(q10;q10). The second case, a patient with acute myeloid leukemia, had multiple Robertsonian translocations: der(15)t(13;15)(q11.1;p11.1), der(14;22)(q10;q10), and dic(21;22)(p11.1;p11.1). Acquired multiple Robertsonian translocations have not been reported previously in leukemia. |
| doi_str_mv | 10.1016/S0165-4608(01)00478-2 |
| format | Article |
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The first case was a patient with chronic lymphocytic leukemia, who was found to have a rare Robertsonian translocation der(14;15)(q10;q10). The second case, a patient with acute myeloid leukemia, had multiple Robertsonian translocations: der(15)t(13;15)(q11.1;p11.1), der(14;22)(q10;q10), and dic(21;22)(p11.1;p11.1). Acquired multiple Robertsonian translocations have not been reported previously in leukemia.</description><subject>Acute Disease</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Chromosomes, Human, Pair 13</subject><subject>Chromosomes, Human, Pair 14</subject><subject>Chromosomes, Human, Pair 15</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemia, Lymphocytic, Chronic, B-Cell - genetics</subject><subject>Leukemia, Myeloid - genetics</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. 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Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Translocation, Genetic</topic><toplevel>online_resources</toplevel><creatorcontrib>Chinnappan, Dharmaraj</creatorcontrib><creatorcontrib>Philip, Abraham</creatorcontrib><creatorcontrib>Wu, Xiao</creatorcontrib><creatorcontrib>Pan, Agen</creatorcontrib><creatorcontrib>Wyandt, Herman E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer genetics and cytogenetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chinnappan, Dharmaraj</au><au>Philip, Abraham</au><au>Wu, Xiao</au><au>Pan, Agen</au><au>Wyandt, Herman E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Acquired Robertsonian translocations in two leukemia patients</atitle><jtitle>Cancer genetics and cytogenetics</jtitle><addtitle>Cancer Genet Cytogenet</addtitle><date>2001-12-01</date><risdate>2001</risdate><volume>131</volume><issue>2</issue><spage>104</spage><epage>108</epage><pages>104-108</pages><issn>0165-4608</issn><eissn>1873-4456</eissn><coden>CGCYDF</coden><abstract>Robertsonian translocations were observed in two leukemia patients. 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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Acute Disease Aged Biological and medical sciences Chromosomes, Human, Pair 13 Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 15 Hematologic and hematopoietic diseases Humans Leukemia, Lymphocytic, Chronic, B-Cell - genetics Leukemia, Myeloid - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Middle Aged Translocation, Genetic |
| title | Acquired Robertsonian translocations in two leukemia patients |
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