Nonreceptor Tyrosine Phosphatases in Cellular Signaling: Regulation of Mitogen-Activated Protein Kinases
A large number of nonreceptor tyrosine phosphatases have been shown to specifically regulate mitogen-activated protein kinase (MAPK) signaling. Zhan, et al, provide an overview of MAPK signaling and then discuss the functions of intracellular PTPases, particularly the functions of PTPases in MAPK re...
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Veröffentlicht in: | Chemical reviews 2001-08, Vol.101 (8), p.2477-2496 |
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creator | Zhan, Xiao-Li Wishart, Matthew J Guan, Kun-Liang |
description | A large number of nonreceptor tyrosine phosphatases have been shown to specifically regulate mitogen-activated protein kinase (MAPK) signaling. Zhan, et al, provide an overview of MAPK signaling and then discuss the functions of intracellular PTPases, particularly the functions of PTPases in MAPK regulation. |
doi_str_mv | 10.1021/cr000245u |
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source | MEDLINE; American Chemical Society Journals |
subjects | Animals Biochemistry Cells Mitogen-Activated Protein Kinases - metabolism Protein Tyrosine Phosphatases - metabolism Proteins Signal Transduction Substrate Specificity |
title | Nonreceptor Tyrosine Phosphatases in Cellular Signaling: Regulation of Mitogen-Activated Protein Kinases |
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