Nonreceptor Tyrosine Phosphatases in Cellular Signaling:  Regulation of Mitogen-Activated Protein Kinases

A large number of nonreceptor tyrosine phosphatases have been shown to specifically regulate mitogen-activated protein kinase (MAPK) signaling. Zhan, et al, provide an overview of MAPK signaling and then discuss the functions of intracellular PTPases, particularly the functions of PTPases in MAPK re...

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Veröffentlicht in:Chemical reviews 2001-08, Vol.101 (8), p.2477-2496
Hauptverfasser: Zhan, Xiao-Li, Wishart, Matthew J, Guan, Kun-Liang
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container_title Chemical reviews
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creator Zhan, Xiao-Li
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description A large number of nonreceptor tyrosine phosphatases have been shown to specifically regulate mitogen-activated protein kinase (MAPK) signaling. Zhan, et al, provide an overview of MAPK signaling and then discuss the functions of intracellular PTPases, particularly the functions of PTPases in MAPK regulation.
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subjects Animals
Biochemistry
Cells
Mitogen-Activated Protein Kinases - metabolism
Protein Tyrosine Phosphatases - metabolism
Proteins
Signal Transduction
Substrate Specificity
title Nonreceptor Tyrosine Phosphatases in Cellular Signaling:  Regulation of Mitogen-Activated Protein Kinases
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