Protein Phosphatases−A Phylogenetic Perspective

Protein Phosphatases−A Phylogenetic Perspective

The complex and cosmopolitan distribution of the agents that effect regulatory protein phosphorylation-dephosphorylation have thrown conventional models for its origin and development into a state of flux. Kennelly surveys the current state of knowledge concerning the phylogenetic distribution of th...

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Veröffentlicht in:Chemical reviews 2001-08, Vol.101 (8), p.2291-2312
1. Verfasser: Kennelly, Peter J
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
Biochemistry
Molecular Weight
Phosphates
Phosphoprotein Phosphatases - chemistry
Phosphoprotein Phosphatases - classification
Phosphoprotein Phosphatases - metabolism
Phylogeny
Protein Conformation
Proteins
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Beschreibung
Zusammenfassung:The complex and cosmopolitan distribution of the agents that effect regulatory protein phosphorylation-dephosphorylation have thrown conventional models for its origin and development into a state of flux. Kennelly surveys the current state of knowledge concerning the phylogenetic distribution of the major classes of protein phosphatases identified to date and attempts to glean clues from the phylogenetic record.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr0002543