Glycogen Synthase Kinase-3: Properties, Functions, and Regulation
Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase encoded by two isoforms in mammals, termed GSK-3alpha and GSK-3beta. Ali, et al, discuss the biochemical and functional properties of GSK-3 and the recent advances in understanding of the involvement of this unusual enzyme in human path...
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| Veröffentlicht in: | Chemical reviews 2001-08, Vol.101 (8), p.2527-2540 |
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| container_title | Chemical reviews |
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| creator | Ali, Adnan Hoeflich, Klaus P Woodgett, James R |
| description | Glycogen synthase kinase-3 (GSK-3) is a serine-threonine kinase encoded by two isoforms in mammals, termed GSK-3alpha and GSK-3beta. Ali, et al, discuss the biochemical and functional properties of GSK-3 and the recent advances in understanding of the involvement of this unusual enzyme in human patho-physiology. |
| doi_str_mv | 10.1021/cr000110o |
| format | Article |
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| ispartof | Chemical reviews, 2001-08, Vol.101 (8), p.2527-2540 |
| issn | 0009-2665 1520-6890 |
| language | eng |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Animals Biochemistry Calcium-Calmodulin-Dependent Protein Kinases - metabolism Chemicals Glycogen Synthase Kinase 3 Glycogen Synthase Kinases Inflammation - enzymology Mammals Pathology Proteins Signal Transduction |
| title | Glycogen Synthase Kinase-3: Properties, Functions, and Regulation |
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