Diabetic Cataract of the Musk Shrew (Suncus murinus, Insectivora) Exhibiting Spontaneous Non-Insulin Dependent Diabetes Mellitus (NIDDM)

The EDS colony, developed as a new laboratory colony of the musk shrew, is characterized by a high incidence of early-onset spontaneous non-insulin dependent diabates mellitus (NIDDM). In this colony, a few diabetic shrews exhibited a cataract at 1 month after the onset of diabetes, and all diabetic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Experimental Animals 2001, Vol.50(5), pp.431-433
Hauptverfasser: OHNO, Tamio, KITOH, Junzoh, TANAKA, Shin, NISHIMURA, Masahiko, NAMIKAWA, Takao
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The EDS colony, developed as a new laboratory colony of the musk shrew, is characterized by a high incidence of early-onset spontaneous non-insulin dependent diabates mellitus (NIDDM). In this colony, a few diabetic shrews exhibited a cataract at 1 month after the onset of diabetes, and all diabetic shrews had bilateral cataracts at 5 months after the onset of diabetes. In contrast, cataractous animals were never observed among non-diabetic shrews. These results suggest that the cataract in the EDS colony is a diabetic complication.
ISSN:1341-1357
1881-7122
DOI:10.1538/expanim.50.431