Pediatric urolithiasis in southern Israel: the role of uricosuria

We describe three cases of severe obstructive uropathy in children under 2 years of age, due to radiolucent renal stones. Metabolic work-up revealed only normouricemic hyperuricosuria (HU) as the single identifiable risk factor for urolithiasis (UL) in these infants. We reviewed records of 66 cases...

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Veröffentlicht in:	Pediatric nephrology (Berlin, West) West), 2000-10, Vol.14 (12), p.1105-1110
Hauptverfasser:	LANDAU, Daniel, TOVBIN, David, SHALEV, Hanna
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis. Health state Arabs Biological and medical sciences Epidemiology Female General aspects Humans Infant Israel - ethnology Jews Male Medical sciences Prevalence Public health. Hygiene Public health. Hygiene-occupational medicine Risk Factors Ureteral Obstruction - epidemiology Ureteral Obstruction - etiology Uric Acid - urine Urinary Calculi - complications Urinary Calculi - epidemiology Urinary Calculi - urine
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Zusammenfassung:	We describe three cases of severe obstructive uropathy in children under 2 years of age, due to radiolucent renal stones. Metabolic work-up revealed only normouricemic hyperuricosuria (HU) as the single identifiable risk factor for urolithiasis (UL) in these infants. We reviewed records of 66 cases of pediatric UL seen in our service over an 8-year period. UL prevalence was greater for Bedouin than for Jewish children (1.02 vs. 0.13 cases/1,000 inhabitants at risk respectively, P0.6 mg uric acid/dl GFR) was the only biochemical risk factor that differed between Bedouin and Jewish children (mean uric acid excretion index 0.8+/-0.39 vs. 0.55+/-0.26 mg/dl GFR respectively, P
ISSN:	0931-041X 1432-198X
DOI:	10.1007/s004670000328