Constituents from the Stem and Root of Aristolochia kaempferi

Three new phenanthrene derivatives, aristoliukine-C, aristofolin-E and aristolochic acid-Ia methyl ester, and one new sesquiterpene, madolin-P, together with 58 known compounds were isolated from the stem and root of Aristolochia kaempferi. The structures of these compounds were determined by spectr...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2000/10/01, Vol.23(10), pp.1216-1219
Hauptverfasser:	WU, Tian-Shung, LEU, Yann-Lii, CHAN, Yu-Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology antiplatelet agent aristofolin-E aristoliukine-C Aristolochia kaempferi Aristolochiaceae aristolochic acid-Ia methyl ester Biological and medical sciences cytotoxic agent Drug Screening Assays, Antitumor General pharmacology Humans In Vitro Techniques madolin-P Magnetic Resonance Spectroscopy Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phenanthrenes - analysis Phenanthrenes - isolation & purification Plant Extracts - chemistry Plant Extracts - pharmacology Plant Roots - chemistry Plant Stems - chemistry Plants, Medicinal - chemistry Platelet Aggregation Inhibitors - pharmacology sesquiterpene Sesquiterpenes - analysis Sesquiterpenes - isolation & purification Spectrometry, Mass, Fast Atom Bombardment Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Taiwan
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Beschreibung
Zusammenfassung:	Three new phenanthrene derivatives, aristoliukine-C, aristofolin-E and aristolochic acid-Ia methyl ester, and one new sesquiterpene, madolin-P, together with 58 known compounds were isolated from the stem and root of Aristolochia kaempferi. The structures of these compounds were determined by spectral analysis. The cytotoxicity and antiplatelet activity of the isolated compounds are also discussed.
ISSN:	0918-6158 1347-5215
DOI:	10.1248/bpb.23.1216