Resistance of mice exposed to whole-body irradiation to transplanted hemopoietic cells modified with RNA preparations

Resistance of mice exposed to whole-body irradiation to transplanted hemopoietic cells modified with RNA preparations

The resistance of irradiated mice to bone marrow grafts treated with RNA from the liver of syngenic, allogenic, or xenogenic (rat) species was studied. Syngenic recipients developed resistance to grafts treated with allogenic RNA. The resistance to allografts increased after treatment with xenogenic...

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Veröffentlicht in:Bulletin of experimental biology and medicine 2000-06, Vol.129 (6), p.571-574
Hauptverfasser: Nikolin, V P, Il'inskaya, S I, Popova, N A, Karakin, E I
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Bone marrow
Bone Marrow Cells - drug effects
Bone Marrow Cells - metabolism
Bone Marrow Transplantation
Graft Survival
Graft vs Host Reaction
Liver
Male
Mice
Mice, Inbred A
Mice, Inbred BALB C
Mice, Inbred Strains
Radiation
Rats
Rats, Wistar
RNA
RNA - genetics
RNA - immunology
RNA - isolation & purification
RNA - pharmacology
Syngeneic grafts
Transplantation, Heterologous
Transplantation, Homologous
Whole-Body Irradiation
Xenografts
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Zusammenfassung:The resistance of irradiated mice to bone marrow grafts treated with RNA from the liver of syngenic, allogenic, or xenogenic (rat) species was studied. Syngenic recipients developed resistance to grafts treated with allogenic RNA. The resistance to allografts increased after treatment with xenogenic RNA, whereas treatment of allo- and xenografts with syngenic RNA facilitated their take.
ISSN:0007-4888
1573-8221
DOI:10.1007/BF02434880