Bedside coagulometry during intravenous heparin therapy after coronary angioplasty

In order to assess the applicability of a bedside coagulometer for measurement of b-APTT, serial blood samples were obtained from 20 patients receiving intravenous heparin treatment following PTCA, and from 5 healthy volunteers. B-APTT was analysed bedside on the Hemochron coagulometer; p-APTT and p...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2001-10, Vol.12 (2), p.157-163
Hauptverfasser:	SCHROEDER, Anne Pauline, KNUDSEN, Lars Lyhne, HUSTED, Steen E, KNUDSEN, Lars, INGERSLEV, Jørgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Angioplasty, Balloon, Coronary Biological and medical sciences Blood Coagulation Tests - instrumentation Blood Coagulation Tests - standards Diseases of the cardiovascular system Drug Monitoring - methods Drug Monitoring - standards Female Heparin - administration & dosage Heparin - blood Heparin - pharmacokinetics Humans Infusions, Intravenous Male Medical sciences Middle Aged Partial Thromboplastin Time Point-of-Care Systems Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Regression Analysis Reproducibility of Results
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Zusammenfassung:	In order to assess the applicability of a bedside coagulometer for measurement of b-APTT, serial blood samples were obtained from 20 patients receiving intravenous heparin treatment following PTCA, and from 5 healthy volunteers. B-APTT was analysed bedside on the Hemochron coagulometer; p-APTT and p-heparin, measured as factor anti-Xa activity, were analysed ex-vivo in the laboratory. B-APTT values, determined by the Hemochron coagulometer, were closely correlated to p-heparin (r=0.83, p
ISSN:	0929-5305 1573-742X
DOI:	10.1023/A:1012923505198