Methods of determining and evaluating reversibility of airway obstruction

The laboratory measurements of the reversibility of airways obstruction is assessed by performing pulmonary function tests before and after administration of bronchodilators. Controversial issues relating to bronchodilator testing include: selection of bronchodilator, dosage, pattern of inhalation of the drug, timing of the postbronchodilator test, physiologic tests utilized, criteria for the significant response, and the role of glucocorticoids in the relief of airways obstruction.