Relationship of tumoral hyaluronic acid and cathepsin D contents with histological type of gastric carcinoma

The aim of this work was to evaluate the cytosolic contents of hyaluronic acid (HA) and cathepsin D (CatD) in gastric carcinomas and their possible relationships with the clinicopathological parameters of the tumors. Our study demonstrated a wide variability in the cytosolic levels of HA (mean +/- S...

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Veröffentlicht in:	The International journal of biological markers 2000-07, Vol.15 (3), p.215-218
Hauptverfasser:	GARCIA, I, VIZOSO, F, SUAREZ, C, SANZ, L, RODRIGUEZ, J. C, ROIZ, C, GARCIA-MUNIZ, J. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Cathepsin D - analysis Female Gastroenterology. Liver. Pancreas. Abdomen Humans Hyaluronic Acid - analysis Male Medical sciences Middle Aged Stomach Neoplasms - chemistry Stomach Neoplasms - pathology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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Zusammenfassung:	The aim of this work was to evaluate the cytosolic contents of hyaluronic acid (HA) and cathepsin D (CatD) in gastric carcinomas and their possible relationships with the clinicopathological parameters of the tumors. Our study demonstrated a wide variability in the cytosolic levels of HA (mean +/- SEM: 3748 +/- 411 ng/mg protein) and cathepsin D (52 +/- 4 pmol/mg protein) in the tumors of 78 gastric cancer patients. In addition, the tumoral contents of HA and CatD were significantly higher (p
ISSN:	0393-6155 1724-6008
DOI:	10.1177/172460080001500302