XPS and surface-MALDI-MS characterisation of worn HEMA-based contact lenses

XPS and surface-MALDI-MS characterisation of worn HEMA-based contact lenses

XPS and MALDI-MS were used to analyse initial adsorption events in the fouling of HEMA-based contact lenses. All of the lenses tested accumulated tear film deposits within 10 min of wear. XPS indicated the presence of mainly proteinaceous deposits, with indications of some contributions by mucins or...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biomaterials 2001-12, Vol.22 (24), p.3295-3304
Hauptverfasser: McArthur, Sally L, McLean, Keith M, St. John, Heather A.W, Griesser, Hans J
Format: Artikel
Sprache:eng
Schlagworte:
Adsorption
Biocompatible Materials - chemistry
Contact Lenses, Hydrophilic
HEMA contact lens
Humans
Hydrogels
Interface conversion
MALDI-MS
Materials Testing
Methacrylates - chemistry
Polyhydroxyethyl Methacrylate - analogs & derivatives
Polyhydroxyethyl Methacrylate - chemistry
Protein fouling
Proteins - chemistry
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Spectrometry, X-Ray Emission
Surface Properties
Tears - chemistry
XPS
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:XPS and MALDI-MS were used to analyse initial adsorption events in the fouling of HEMA-based contact lenses. All of the lenses tested accumulated tear film deposits within 10 min of wear. XPS indicated the presence of mainly proteinaceous deposits, with indications of some contributions by mucins or lipids on some lenses and the nature of the deposit being influenced by the lens chemistry. MALDI-MS detected the presence of surface-adsorbed species with molecular weights
ISSN:0142-9612
1878-5905
DOI:10.1016/S0142-9612(01)00166-1