Properties of Small Molecules Affecting Insulin Receptor Function

Small molecules with insulin mimetic effects and oral availability are of interest for potential substitution of insulin injections in the treatment of diabetes. We have searched databases for compounds capable of mimicking one epitope of the insulin molecule known to be involved in binding to the i...

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Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Easton) 2001-11, Vol.40 (45), p.13520-13528
Hauptverfasser:	Schlein, Morten, Ludvigsen, Svend, Olsen, Helle B, Andersen, Asser S, Danielsen, Gillian M, Kaarsholm, Niels C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cricetinae Databases, Factual Eosine Yellowish-(YS) - chemistry Eosine Yellowish-(YS) - metabolism Erythrosine - chemistry Erythrosine - metabolism Fluorescein - chemistry Fluorescein - metabolism Humans Insulin - chemistry Insulin - metabolism Magnetic Resonance Spectroscopy Models, Molecular Phenolsulfonphthalein - chemistry Phenolsulfonphthalein - metabolism Receptor, Insulin - chemistry Receptor, Insulin - drug effects Receptor, Insulin - metabolism Spectrometry, Fluorescence Spectrophotometry, Ultraviolet
Online-Zugang:	Volltext
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