Evaluation of the Epidermal Growth Factor Receptor (EGFR) and c-erbB-2 in Superspreading-type and Penetrating-type Gastric Carcinoma

Evaluation of the Epidermal Growth Factor Receptor (EGFR) and c-erbB-2 in Superspreading-type and Penetrating-type Gastric Carcinoma

The expression of epidermal growth factor (EGF), epidermal growth factor receptor (EGFR), transforming growth factor α (TGF α), and of c-erbB-2 was immunohistochemically investigated in resected gastric carcinoma (in 39 cases of superspreading type and in 11 cases of penetrating type), to understand...

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Veröffentlicht in:Kurume medical journal 2001/09/14, Vol.48(3), pp.197-200
Hauptverfasser: AOYAGI, KEISHIRO, KOHFUJI, KIKUO, YANO, SHOJIRO, MURAKAMI, NAOTAKA, MIYAGI, MOTOSHI, TAKEDA, JINRYO, SHIROUZU, KAZUO
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
c-erbB-2
Epidermal Growth Factor - analysis
Female
gastric carcinoma
growth factor
Humans
Immunohistochemistry
Male
Middle Aged
penetrating type
Receptor, Epidermal Growth Factor - analysis
Receptor, ErbB-2 - analysis
Stomach Neoplasms - chemistry
Stomach Neoplasms - pathology
superspreading type
Transforming Growth Factor alpha - analysis
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Zusammenfassung:The expression of epidermal growth factor (EGF), epidermal growth factor receptor (EGFR), transforming growth factor α (TGF α), and of c-erbB-2 was immunohistochemically investigated in resected gastric carcinoma (in 39 cases of superspreading type and in 11 cases of penetrating type), to understand the differential biological features of these two types of gastric carcinoma. EGF, EGFR and c-erbB-2 positive cases were preferentially found in penetrating type rather than in superspreading type (p
ISSN:0023-5679
1881-2090
DOI:10.2739/kurumemedj.48.197