The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase

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Veröffentlicht in:	Pharmaceutical research 2001-09, Vol.18 (9), p.1327-1330
Hauptverfasser:	LILI LU, LEONESSA, Fabio, BAYNHAM, Michael T, CLARKE, Robert, GIMENEZ, Francois, PHAM, Yen-Thu, ROUX, Francoise, WAINER, Irving W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - chemistry Antimalarials - pharmacokinetics Antiparasitic agents ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism Binding Sites Binding, Competitive - drug effects Biological and medical sciences Chromatography Chromatography, Affinity Cyclosporine - metabolism Glycerol Glycoproteins Humans Ligands Medical sciences Mefloquine - chemistry Mefloquine - pharmacokinetics Pharmacology. Drug treatments Protein Binding Stereoisomerism Vinblastine - metabolism
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