Surface plasmon resonance sensor using molecularly imprinted polymer for detection of sialic acid
A surface plasmon resonance (SPR) sensor using a molecularly imprinted polymer-coated sensor chip for the detection of sialic acid was developed. The thinly coated polymer was prepared by co-polymerizing N, N, N-trimethylaminoethyl methacrylate, 2-hydroxyethyl methacrylate and ethyleneglycol dimetha...
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Veröffentlicht in: | Biosensors & bioelectronics 2001-12, Vol.16 (9), p.1059-1062 |
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container_title | Biosensors & bioelectronics |
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creator | Kugimiya, Akimitsu Takeuchi, Toshifumi |
description | A surface plasmon resonance (SPR) sensor using a molecularly imprinted polymer-coated sensor chip for the detection of sialic acid was developed. The thinly coated polymer was prepared by co-polymerizing
N,
N,
N-trimethylaminoethyl methacrylate, 2-hydroxyethyl methacrylate and ethyleneglycol dimethacrylate in the presence of
p-vinylbenzeneboronic acid ester with sialic acid. The sensor showed a selective response to ganglioside of which sialic acid is located at the non-reducing end and gave a linear relationship from 0.1 to 1.0 mg of ganglioside. |
doi_str_mv | 10.1016/S0956-5663(01)00227-5 |
format | Article |
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N,
N,
N-trimethylaminoethyl methacrylate, 2-hydroxyethyl methacrylate and ethyleneglycol dimethacrylate in the presence of
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N,
N,
N-trimethylaminoethyl methacrylate, 2-hydroxyethyl methacrylate and ethyleneglycol dimethacrylate in the presence of
p-vinylbenzeneboronic acid ester with sialic acid. The sensor showed a selective response to ganglioside of which sialic acid is located at the non-reducing end and gave a linear relationship from 0.1 to 1.0 mg of ganglioside.</description><subject>Analytical biochemistry: general aspects, technics, instrumentation</subject><subject>Analytical, structural and metabolic biochemistry</subject><subject>Biological and medical sciences</subject><subject>Biomimetic sensor</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>G(M1) Ganglioside - analysis</subject><subject>G(M1) Ganglioside - chemistry</subject><subject>Ganglioside</subject><subject>Molecular imprinting</subject><subject>N-Acetylneuraminic Acid - analysis</subject><subject>Polymers - chemistry</subject><subject>Sialic acid</subject><subject>Surface plasmon resonance</subject><subject>Surface Plasmon Resonance - instrumentation</subject><subject>Surface Plasmon Resonance - methods</subject><issn>0956-5663</issn><issn>1873-4235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LHTEUhkNp0av1J7RkY7GL0SQzmUxWpUi1gtCFdh1ykxOJZCbXnBnh_nuj91KXXR04PO_5eAj5wtk5Z7y_uGNa9o3s-_aM8e-MCaEa-YGs-KDaphOt_EhW_5BDcoT4yBhTXLMDcsh5r7QY9IrYu6UE64BuksUxT7QA5slOtYMwYS50wTg90DEncEuyJW1pHDclTjN4uslpO0KhoXIeZnBzrCNyoBhtio5aF_1n8inYhHCyr8fk79Wv-8vfze2f65vLn7eNazWfGwjcDZ3veK81tFoILkGuO_AQQGrlwa-D7HqlpB0sd4IpGwawqhdskGvp2mPybTd3U_LTAjibMaKDlOwEeUGjhGg73g0VlDvQlYxYIJj6zmjL1nBmXt2aN7fmVZxh3Ly5NbLmvu4XLOsR_HtqL7MCp3vAorMplKox4jtXt3f13Mr92HFQdTxHKAZdhKrcx1IVGp_jf055Adz2l9A</recordid><startdate>20011201</startdate><enddate>20011201</enddate><creator>Kugimiya, Akimitsu</creator><creator>Takeuchi, Toshifumi</creator><general>Elsevier B.V</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20011201</creationdate><title>Surface plasmon resonance sensor using molecularly imprinted polymer for detection of sialic acid</title><author>Kugimiya, Akimitsu ; Takeuchi, Toshifumi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-ef1c84d41699e392215e5b4edefe597dedbf546775a8a1c207af8ea762085b5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Analytical biochemistry: general aspects, technics, instrumentation</topic><topic>Analytical, structural and metabolic biochemistry</topic><topic>Biological and medical sciences</topic><topic>Biomimetic sensor</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>G(M1) Ganglioside - analysis</topic><topic>G(M1) Ganglioside - chemistry</topic><topic>Ganglioside</topic><topic>Molecular imprinting</topic><topic>N-Acetylneuraminic Acid - analysis</topic><topic>Polymers - chemistry</topic><topic>Sialic acid</topic><topic>Surface plasmon resonance</topic><topic>Surface Plasmon Resonance - instrumentation</topic><topic>Surface Plasmon Resonance - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kugimiya, Akimitsu</creatorcontrib><creatorcontrib>Takeuchi, Toshifumi</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Biosensors & bioelectronics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kugimiya, Akimitsu</au><au>Takeuchi, Toshifumi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surface plasmon resonance sensor using molecularly imprinted polymer for detection of sialic acid</atitle><jtitle>Biosensors & bioelectronics</jtitle><addtitle>Biosens Bioelectron</addtitle><date>2001-12-01</date><risdate>2001</risdate><volume>16</volume><issue>9</issue><spage>1059</spage><epage>1062</epage><pages>1059-1062</pages><issn>0956-5663</issn><eissn>1873-4235</eissn><abstract>A surface plasmon resonance (SPR) sensor using a molecularly imprinted polymer-coated sensor chip for the detection of sialic acid was developed. The thinly coated polymer was prepared by co-polymerizing
N,
N,
N-trimethylaminoethyl methacrylate, 2-hydroxyethyl methacrylate and ethyleneglycol dimethacrylate in the presence of
p-vinylbenzeneboronic acid ester with sialic acid. The sensor showed a selective response to ganglioside of which sialic acid is located at the non-reducing end and gave a linear relationship from 0.1 to 1.0 mg of ganglioside.</abstract><cop>Lausanne</cop><pub>Elsevier B.V</pub><pmid>11679289</pmid><doi>10.1016/S0956-5663(01)00227-5</doi><tpages>4</tpages></addata></record> |
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issn | 0956-5663 1873-4235 |
language | eng |
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source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Analytical biochemistry: general aspects, technics, instrumentation Analytical, structural and metabolic biochemistry Biological and medical sciences Biomimetic sensor Fundamental and applied biological sciences. Psychology G(M1) Ganglioside - analysis G(M1) Ganglioside - chemistry Ganglioside Molecular imprinting N-Acetylneuraminic Acid - analysis Polymers - chemistry Sialic acid Surface plasmon resonance Surface Plasmon Resonance - instrumentation Surface Plasmon Resonance - methods |
title | Surface plasmon resonance sensor using molecularly imprinted polymer for detection of sialic acid |
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