Response of metastatic epidermoid anal cancer to single agent irinotecan: a case report

We report a case of a patient affected by epidermoid anal cancer who had hepatic progression after standard therapy with the Nigro regimen (fluorouracil and mitomycin C plus radiotherapy). This is an uncommon neoplasm against which only few chemotherapeutic agents have been tested. In our patient sa...

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Veröffentlicht in:	Tumori 2001-01, Vol.87 (1), p.58-59
Hauptverfasser:	Grifaichi, F, Padovani, A, Romeo, F, Trinca, C, Moscetti, L, Cortesi, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - therapeutic use Anus Neoplasms - drug therapy Anus Neoplasms - pathology Camptothecin - analogs & derivatives Camptothecin - therapeutic use Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - secondary Female Humans Middle Aged Treatment Outcome
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Zusammenfassung:	We report a case of a patient affected by epidermoid anal cancer who had hepatic progression after standard therapy with the Nigro regimen (fluorouracil and mitomycin C plus radiotherapy). This is an uncommon neoplasm against which only few chemotherapeutic agents have been tested. In our patient salvage treatment with low dose irinotecan resulted in a partial response.
ISSN:	0300-8916 2038-2529
DOI:	10.1177/030089160108700113