New Allene Synthesis via Carbocupration−Zinc Carbenoid Homologation and β-Elimination Sequence

New Allene Synthesis via Carbocupration−Zinc Carbenoid Homologation and β-Elimination Sequence

Polysubstituted propadienes are obtained in good to excellent yields by the consecutive carbocupration−homologation−β-elimination reactions on the easily accessible alkynyl sulfoxides or sulfones. This one-pot reaction also allows the preparation of functionalized allenes.

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Veröffentlicht in:Organic letters 2000-09, Vol.2 (18), p.2849-2852
Hauptverfasser: Varghese, Jos P, Knochel, Paul, Marek, Ilan
Format: Artikel
Sprache:eng
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Zusammenfassung:Polysubstituted propadienes are obtained in good to excellent yields by the consecutive carbocupration−homologation−β-elimination reactions on the easily accessible alkynyl sulfoxides or sulfones. This one-pot reaction also allows the preparation of functionalized allenes.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol006276t