Discovery of Potent Antagonists of the Interaction between Human Double Minute 2 and Tumor Suppressor p53

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of medicinal chemistry 2000-08, Vol.43 (17), p.3205-3208
Hauptverfasser:	García-Echeverría, Carlos, Chène, Patrick, Blommers, Marcel J. J, Furet, Pascal
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Antineoplastic agents Biological and medical sciences Crystallography, X-Ray General aspects Humans Ligands Medical sciences Models, Molecular Nuclear Proteins Peptide Fragments - chemistry Peptides - chemical synthesis Peptides - chemistry Pharmacology. Drug treatments Proto-Oncogene Proteins - antagonists & inhibitors Proto-Oncogene Proteins - chemistry Proto-Oncogene Proteins - metabolism Proto-Oncogene Proteins c-mdm2 Structure-Activity Relationship Tumor Suppressor Protein p53 - antagonists & inhibitors Tumor Suppressor Protein p53 - chemistry Tumor Suppressor Protein p53 - metabolism
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