Molecular biology of Streptococcus pneumoniae: an everlasting challenge
Streptococcus pneumoniae is a model for elucidating: 1) recombination steps of DNA, from its discovery to polarity of integration; 2) long-patch mismatch repair, short-patch repair triggered by A/G and exclusion of deletions; 3) resistance to β-lactam antibiotics; and 4) factors of virulence. Severa...
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Veröffentlicht in: | Research in microbiology 2000-07, Vol.151 (6), p.407-411 |
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creator | Sicard, Michel Gasc, Anne Marie Giammarinaro, Philippe Lefrançois, Jacques Pasta, Frank Samrakandi, Mustapha |
description | Streptococcus pneumoniae is a model for elucidating: 1) recombination steps of DNA, from its discovery to polarity of integration; 2) long-patch mismatch repair, short-patch repair triggered by A/G and exclusion of deletions; 3) resistance to β-lactam antibiotics; and 4) factors of virulence. Several of these topics remain a challenge for future investigations. |
doi_str_mv | 10.1016/S0923-2508(00)00176-5 |
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subjects | Animals antibiotic resistance Bacteriology Base Pair Mismatch beta-Lactam Resistance Biological and medical sciences DNA Repair Fundamental and applied biological sciences. Psychology Genetics Mice Microbiology Models, Genetic Pneumococcal Infections - microbiology recombination Recombination, Genetic Streptococcus pneumoniae Streptococcus pneumoniae - genetics Streptococcus pneumoniae - pathogenicity Virulence |
title | Molecular biology of Streptococcus pneumoniae: an everlasting challenge |
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