Composition and Antimicrobial Activity of the Essential Oil of Achillea multifida

Abstract The composition of the water-distilled essential oil of ACHILLEA MULTIFIDA (DC.) Boiss. (Compositae) was analysed by GC and GC/MS. Fifty-eight compounds were identified representing 93.9 % of the total oil. α-Thujone (60.9 %), β-thujone (9.1 %), sabinene (4.1 %) and camphor (3.7 %) were cha...

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Veröffentlicht in:	Planta medica 2002-10, Vol.68 (10), p.941-943
Hauptverfasser:	Başer, K. Hüsnü, Demirci, Betül, Demirci, Fatih, Koçak, Serkan, Akıncı, Çağrı, Malyer, Hulusi, Güleryüz, Gürcan
Format:	Artikel
Sprache:	eng
Schlagworte:	Achillea Anti-Bacterial Agents Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Candida albicans - drug effects Gas Chromatography-Mass Spectrometry Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Humans Letter Microbial Sensitivity Tests Phytotherapy Plant Oils - chemistry Plant Oils - pharmacology
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Zusammenfassung:	Abstract The composition of the water-distilled essential oil of ACHILLEA MULTIFIDA (DC.) Boiss. (Compositae) was analysed by GC and GC/MS. Fifty-eight compounds were identified representing 93.9 % of the total oil. α-Thujone (60.9 %), β-thujone (9.1 %), sabinene (4.1 %) and camphor (3.7 %) were characterised as the main constituents. The essential oil was tested for its antimicrobial activity using a micro-dilution assay resulting in the inhibition (MIC: 62.5 - 250 μg/ml) of human pathogenic bacteria and yeast.
ISSN:	0032-0943 1439-0221
DOI:	10.1055/s-2002-34923