Sudden death due to cardiovascular disorders: a review of the studies on the medico-legal cases in Tokyo

The Tokyo Metropolitan Government has a medical examiner system, in which all cadavers classified as “unusual death” in the city of Tokyo should be examined, and if necessary, autopsied to determine the cause of death. Of about 10, 000 unusual deaths examined per year, two thirds are usu-ally determined to have died of natural causes. The most common cause of sudden natural death is ischemic heart disease, especially acute myocardial infarction. Pathological examination, however, proves acute myocardial ischemia in only one third of autopsies. Subarachnoid hemorrhage and intra-cerebral hemorrhage, acute myocarditis and cardiomyopathies and aortic dissection/aneurysm as well as pulmonary thromboembolism are frequent causes of death in medical examiner cases. Both patholog-ical and socio-medical problems associated with these diseases are discussed. (Keio J Med 50 (3): 175-181, September 2001)