Cytokines involved in the immunosuppressor period in experimental fasciolosis in rats

Cytokines involved in the immunosuppressor period in experimental fasciolosis in rats

The aim of this study was to evaluate the kinetics of the cytokines interferon-γ, interleukin-2, interleukin-10 and interleukin-4 produced by spleen mononuclear cells stimulated by Con A during an experimental infection in rats with Fasciola hepatica. The proliferative response to Con A of Spm cells...

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Veröffentlicht in:International journal for parasitology 2001-11, Vol.31 (13), p.1467-1473
Hauptverfasser: Cervi, L, Cejas, H, Masih, Diana T
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Concanavalin A - immunology
Cytokine
Cytokines - biosynthesis
Cytokines - blood
Experimental helminthic diseases. Models
Fasciola hepatica
Fasciola hepatica - immunology
Fasciolahepatica
Fascioliasis - blood
Fascioliasis - immunology
fasciolosis
Female
g-Interferon
Helminthic diseases
Histocytochemistry
Immunosuppression
Infection
Infectious diseases
Interferon-gamma - biosynthesis
Interferon-gamma - blood
Interleukins - biosynthesis
Interleukins - blood
Leukocytes, Mononuclear - immunology
Leukocytes, Mononuclear - metabolism
Liver - parasitology
Liver - pathology
Macrophages, Peritoneal - immunology
Medical sciences
nitric oxide
Nitric Oxide - analysis
Nitric Oxide - biosynthesis
Parasitic diseases
Rats
Rats, Wistar
Spleen - cytology
Spleen - immunology
Spleen - metabolism
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Beschreibung
Zusammenfassung:The aim of this study was to evaluate the kinetics of the cytokines interferon-γ, interleukin-2, interleukin-10 and interleukin-4 produced by spleen mononuclear cells stimulated by Con A during an experimental infection in rats with Fasciola hepatica. The proliferative response to Con A of Spm cells from rats infected with F. hepatica was significantly decreased on day 7 post-infection ( P
ISSN:0020-7519
1879-0135
DOI:10.1016/S0020-7519(01)00275-2