Tris-benzimidazole derivatives : Design, synthesis and DNA sequence recognition

Two tris-benzimidazole derivatives have been designed and synthesized based on the known structures of the bis-benzimidazole stain Hoechst 33258 complexed to short oligonucleotide duplexes derived from single crystal X-ray studies and from NMR. In both derivatives the phenol group has been replaced...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bioorganic & medicinal chemistry 2001-11, Vol.9 (11), p.2905-2919
Hauptverfasser:	JI, Yu-Hua, BUR, Daniel, HÄSLER, Walter, SCHMITT, Valérie Runtz, DORN, Arnulf, BAILLY, Christian, WARING, Michael J, HOCHSTRASSER, Remo, LEUPIN, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Benzimidazoles - chemical synthesis Benzimidazoles - metabolism Binding Sites Biological and medical sciences Bisbenzimidazole Circular Dichroism DNA Footprinting Drug Design Fluorescent Dyes Fundamental and applied biological sciences. Psychology Interactions. Associations Intermolecular phenomena Molecular biophysics Molecular Structure Oligodeoxyribonucleotides - chemistry Oligodeoxyribonucleotides - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!