Spontaneous Deposition of Water-Soluble Substances into Microcapsules: Phenomenon, Mechanism, and Application
Water‐soluble species can be deposited into preformed, multilayered polyelectrolyte capsules, templated onto melamine formaldehyde particles, with high integrity. Efficient encapsulation of albumin within capsules formed from a poly(styrene sulfonate)/poly(allylamine hydrochloride) composite was ach...
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| Veröffentlicht in: | Angewandte Chemie International Edition 2002-10, Vol.41 (20), p.3789-3793 |
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| container_issue | 20 |
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| container_title | Angewandte Chemie International Edition |
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| creator | Gao, Changyou Donath, Edwin Möhwald, Helmuth Shen, Jiacong |
| description | Water‐soluble species can be deposited into preformed, multilayered polyelectrolyte capsules, templated onto melamine formaldehyde particles, with high integrity. Efficient encapsulation of albumin within capsules formed from a poly(styrene sulfonate)/poly(allylamine hydrochloride) composite was achieved at pH values below the isoelctric point of the protein through spontaneous deposition (see picture). |
| doi_str_mv | 10.1002/1521-3773(20021018)41:20<3789::AID-ANIE3789>3.0.CO;2-D |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1433-7851 |
| ispartof | Angewandte Chemie International Edition, 2002-10, Vol.41 (20), p.3789-3793 |
| issn | 1433-7851 1521-3773 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72189041 |
| source | MEDLINE; Wiley Journals |
| subjects | Adsorption Animals Biopolymers - pharmacokinetics capsules Capsules - chemical synthesis Capsules - chemistry Colloids Diffusion Drug Carriers - chemical synthesis Drug Carriers - chemistry Humans layered compounds Particle Size polyelectrolytes Polymers self-deposition Serum Albumin - pharmacokinetics Solubility |
| title | Spontaneous Deposition of Water-Soluble Substances into Microcapsules: Phenomenon, Mechanism, and Application |
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